Thyroid sabiston
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Q1           Score:  12.5
 patients with large goiters
 patients who are pregnant
 may become pregnant within the next 6 months
 breastfeeding mothers
 patients with a thyroid nodule concerning for malignancy,
Q2           Score:  12.5
 The action of thyroid hormones in the periphery consists predominantly of the interaction of T3 with the nuclear TR,
 The β form of TR is contained within the liver; the central nervous system contains predominantly an α form of TR
 T4 acts on the pituitary by regulating tranScription of the genes for the α and β subunits of TSH, which results in TSH secretion.
 T3 affects cardiac contractility by regulating the tranScription of myosin heavy chain production in cardiac muscle.
Q3           Score:  12.5
 oral contraceptives,
 heroin or methadone
 anabolic steroids
 corticosteroids
 nicotinic acid
Q4           Score:  12.5
 chronic deficient iodine intake, production of T4 and T3 is decreased, resulting in gradually increasing thyroid clearance of iodine and decreased renal excretion
 Chronic preferential production of T3 rather than T4 and enhanced peripheral conversion of T4 to T3 occur.
 By making the production of T3 and clearance of the metabolically active hormone as efficient as possible, clinical hypothyroidism is largely avoided by a biochemical pattern of low serum T4 levels with elevated TSH levels and normal or above-normal level
 endemic cretinism. This clinical scenario includes neurologic impairment, stunted growth, mental deficiency, and overt hypothyroidism caused by profound iodine deficiency in utero.
 A, B
 A,B,C
 All
 none
Q5           Score:  12.5
 corticosteroids.
 5-fluorouracil
 nicotinic acid
 clofibrate
Q6           Score:  12.5
 patients with large goiters
 patients who are pregnant
 may become pregnant within the next 6 months
 breastfeeding mothers
 patients with a thyroid nodule concerning for malignancy,
Q7           Score:  12.5
 Relationship to the recurrent laryngeal nerve (RLN).
 Relationship to the Superior laryngeal nerve
 Condensation of connective fascia covering the thyroid glands
 Form from thyroid capsule
Q8           Score:  12.5
 A lingual thyroid is anomaly that occurs when the median thyroid anlage does not descend in a normal fashion.
 thyroid tissue found in lateral neck compartments was known as "lateral aberrant thyroid" represent Differential thyroid carcinoma.
 thyroid tissue found in the neck lateral to the jugular vein represents metastatic deposits from differentiated thyroid carcinoma (DTC), typically papillary cancer
 Calcitonin-producing C cells arise from the fourth pharyngeal pouch and migrate from the neural crest into the thyroid and not originate from endoderm
 This tissue originates in the primitive alimentary tract and consists of cells of epidermal origin


   



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