Final exam لمادة موضوعات مختارة في علم الادوية
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Q1           Score:  0.5
 A- strength of hypothesis
 B- Availibility of target
 C- market prediction
 D- Toxicology
Q2           Score:  0.5
 A- spontaneous
 B- route of exposure
 C- species
 D- sex of test animal formulation
Q3           Score:  0.5
Q4           Score:  0.5
 A- check chemical stability
 B- determine major metabolite
 C- optimize and scale up synthesis and purification
 D- produce GMP batches are required for biological and clinical test
Q5           Score:  0.5
 A- usually placebo controlled
 B- phase IIa is exploratory and phase IIb is confirmatory
 C- the opproxinate number of healthy subject is 50- 500
 D- gives confirmation of clinical dose and regimen for efficacy
Q6           Score:  0.5
 A- chemical development
 B- safety assessment
 C- drug metabolism
 D- all the above
Q7           Score:  0.5
 صح
 خطأ
Q8           Score:  0.5
 A- Aspirin
 B- sulfonamide
 C- chloramphenicol
 D- Tetracycline
Q9           Score:  0.5
 A- digoxin
 B- NSAIDS
 C- Atropine- like drugs
Q10           Score:  0.5
Q11           Score:  0.5
 صح
 خطأ
Q12           Score:  0.5
 A- Health
 B- disease
 C- organization
 D- non the above
Q13           Score:  0.5
Q14           Score:  0.5
 A- gene
 B- protein
 C- cell
 D- tissue
Q15           Score:  0.5
 A- phase -1
 B- phase- 2
Q16           Score:  0.5
 A- digoxin
 B- TCAS
 C- Atropine like drugs
Q17           Score:  0.5
 A- sulfonamide
 B- Aspirin
 C- Mepiridine
 D- Benzodiazepine
Q18           Score:  0.5
 صح
 خطأ
Q19           Score:  0.5
 A- Antibodies
 B- vaccines
 C- enzyme
 D- DNA product
Q20           Score:  0.5
 A- Clark's Rule
 B- Youngs Rule
 C- creatinine clearance
 D- non the above
Q21           Score:  0.5
Q22           Score:  0.5
 A- drug action
 B- cell
 B- tissue
 C- system
Q23           Score:  0.5
 A- treatment of pre- existing chronic disorder
 B- always use drugs which have been widely used
 C- over the counter
 D- drugs for medical condition prior to confirmation of pregnancy
Q24           Score:  0.5
 A- Arthritis
 B-metabolism
 C- peptic ulcer
 D- stroke
Q25           Score:  0.5
 A- producing hypotension
 B- producing hypoglycemia
 C- producing hypertension
 D- producing hyperglycemia
Q26           Score:  0.5
Q27           Score:  0.5
 A- animal
 B- human
 C- in vivo
Q28           Score:  0.5
 A- Elderly people
 B- Infant
 C- they are the major consumer of drug
 D- include polypharmacy
Q29           Score:  0.5
Q30           Score:  0.5
 صح
 خطأ
Q31           Score:  0.5
 صح
 خطأ
Q32           Score:  0.5
 صح
 خطأ
Q33           Score:  0.5
 A- FDA
 B- NMR
 C- IND
Q34           Score:  0.5
Q35           Score:  0.5
Q36           Score:  0.5
 صح
 خطأ
Q37           Score:  0.5
 A- structural
 B- spontaneous
 C- antidotal
 D- route of exposure
Q38           Score:  0.5
 صح
 خطأ
Q39           Score:  0.5
 صح
 خطأ
Q40           Score:  0.5
 A- lethal dose to assayed in the same population
 B- dose required for sub- lethal toxicity
 C- all the above
Q41           Score:  0.5
 صح
 خطأ
Q42           Score:  0.5
 A- nasal hypoplasia
 B- bone stippling on X- Ray
 C- depressed bridge of nose
 D- all the above
 E- non the above
Q43           Score:  0.5
 A- Easily
 B- with difficult
 C- poorly
 D- non of the above
Q44           Score:  0.5
 صح
 خطأ
Q45           Score:  0.5
 A- absorption
 B- medication compliance
 C- reduction in GI motility
 D- Elimination
 E- A+ D
 F- all the above
Q46           Score:  0.5
 صح
 خطأ
Q47           Score:  0.5
 صح
 خطأ
Q48           Score:  0.5
 A- pharmaceutic interaction
 B- pharmacodynamic interaction
 C- pharmacokinetic interaction
Q49           Score:  0.5
 A- albumin
 B- alpha-1 acid glycoproteins
 C- T cell
Q50           Score:  0.5
 A- dose
 B- Age
 C- systemic toxicity
 D- Route
Q51           Score:  0.5
 A- 5- 10 years
 B- 1 month
 C- 15- 25 years
 D- 9 month to 3 years
Q52           Score:  0.5
 صح
 خطأ
Q53           Score:  0.5
 A- vaccination
 B- blood transfusion
 C- transplantation
 D- drug therapy
Q54           Score:  0.5
 A- poly pharmacy
 B- multiple disease state
 C- increase severity of illness
 D- B+ C
 E- all the above
Q55           Score:  0.5
Q56           Score:  0.5
 A- result in polar
 B- water soluble
 C- oxidase
 D- conjugation
Q57           Score:  0.5
 A- urinary retention
 B- hyperglycemia
 C- heart block
 D- GI hemorrhage
Q58           Score:  0.5
 A- pregnancy
 B- cough
 C- diarrhea
 D- heart
Q59           Score:  0.5
 A- In vivo
 B- in human
 C- in animal
 D- in vitro
Q60           Score:  0.5
 A- pharmacodynamic drug- drug interaction
 B- pharmacokinetic drug- drug interaction
 C- pharmaceutic interaction
Q61           Score:  0.5
 صح
 خطأ
Q62           Score:  0.5
Q63           Score:  0.5
 صح
 خطأ
Q64           Score:  0.5
 A- Effect
 B- Efficacy
 C- Effectiveness
 D- BENEFIT
Q65           Score:  0.5
 A- category A
 B- category B
 C- category c
 D- category D
 E- category x
Q66           Score:  0.5
 A- factor including the vascular perfusion
 B- By 6 weeks of age
 C- such as penicillin
 D- are reduced by 50% in premature
Q67           Score:  0.5
 صح
 خطأ
Q68           Score:  0.5
 A- phase I
 B- phase II
 C- phaseI and II and III and IV
 D- phase III
Q69           Score:  0.5
Q70           Score:  0.5
 A- mental retardation
 B- Mutagenesis
 C- is seen in up to 25% of the fetuses with first - trimester exposure to coumarins
 D- carcinogenesis
Q71           Score:  0.5
 صح
 خطأ
Q72           Score:  0.5
 A- fetal period
 B- organogenesis
 C- Blastogenesis
 D- non the above
Q73           Score:  0.5
 صح
 خطأ
Q74           Score:  0.5
 A- mental retardation
 B- Hyperactivity
 C- all the above
 D- non of the above
Q75           Score:  0.5
 A- conducting a clinical trial
 B- Analyzing the outcome of a clinical trial
 C- Givrine permission so clinical trial
 D- non the above
Q76           Score:  0.5
 A- chemical modification of known molecule
 B- biotechnology and cloning
 C- random screening for biological activity of large numbers of natural
 D- all the above
Q77           Score:  0.5
 A- drugs
 B- food additives
 C- cosmetic
 D- pesticide
 E- all of the above
Q78           Score:  0.5
 A- transplant surgery
 B- Apligraf
 C- B cell
 D- influenza
Q79           Score:  0.5
 A- pharmacodynamic
 B- direct toxicity
 C- genotoxicity
 D- all the above
Q80           Score:  0.5
 صح
 خطأ


   



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